Brain Injury & TBI Are A Range of Conditions Rather Than a Single Disease
June 06, 2022
Lately, there have been ground-breaking scientific studies into PTSD and traumatic brain injury (TBI). With such exciting discoveries, it holds out hope for those who suffer from a TBI. Globally, millions sustain severe brain injuries, leaving sufferers disabled or dead. It is a complex disease, and any breakthroughs such as this could pave the way for recovery for millions.
In the last two and a half decades, over $1 billion has been spent on clinical trials for more than thirty drugs for TBI. All have failed to demonstrate a benefit for those with severe brain injuries.
One study examined what occurs to an injured brain at the molecular and cellular levels in the initial critical phase of a severe injury event. This study involved twenty-five adult patients who agreed to a brain biopsy after being injured and a specialized analysis referred to as immunohistochemistry.
Thanks to the investigation, researchers obtained vital information about the severity and type of a patient’s injuries, which could help determine if an individual could benefit from various treatments.
Current neuroimaging tools, such as MRI and CT, do not offer the level of resolution needed to distinguish molecular and cellular changes. This new testing method for the severity of TBIs can show results within 12 hours – a bonus for medical teams and the patient in treating the injury sooner.
Dr. Ping Yip, a lecturer from Queen Mary University, found that conventional drugs were unhelpful for severe TBIs. Brain injuries usually consist of several different conditions.
Since a brain biopsy, also used to diagnose brain cancer, is safe, this technique opens doors to further investigation and refinements to benefit those who suffer from severe TBIs, including veterans.
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